Hong, Hye Ran Jin, Soyoung Koo, Hyun Jung Roh, Jong-Lyel Kim, Jae Seung Cho, Kyung-Ja Choi, Seung-Ho Nam, Soon Yuhl Kim, Sang Yoon 2024-01-20T08:32:57Z 2024-01-20T08:32:57Z 2021-09-02 2014-11 0022-4790 https://pubs.kist.re.kr/handle/201004/126190 Level of Evidence: 2a Background and Objectives: To investigate the role of F-18-FDG PET/CT in tumor staging, extent, and volume measurements in oral cavity squamous cell carcinoma (OSCC) patients with/without dental artifacts on CT or MRI. Methods: This study was conducted in 63 consecutive patients with OSCC who received initial workups including F-18-FDG PET/CT and MRI. The results of the imaging modalities were compared to those of pathology, using McNemar's test and the paired t-test. Results: Thirty-seven patients (59%) had dental or metallic artifacts obscuring primary tumors. F-18-FDG PET/CT scanning was superior to MRI in tumor staging (weighted =0.870 vs. 0.518, P=0.004) in patients with dental artifacts. In addition, F-18-FDG PET/CT scans were more specific than MRI in detecting sublingual gland (P=0.014) and mouth floor (P=0.011) involvement. In patients with dental artifacts, there was a significant discrepancy between primary tumor volume (PTV) measured by pathology and MRI (P=0.018), but not between PTV measured from pathology and F-18-FDG PET/CT at SUV2.5 (P=0.245), which showed the highest intraclass correlation coefficient value (0.860). Conclusion: F-18-FDG PET/CT scans provide accurate tumor staging and volume measurements in OSCC patients with CR/MRI dental artifacts, leading to improved preoperative planning. Level of Evidence: 2b CONDENSED ABSTRACT This study evaluated the clinical value of F-18-FDG PET/CT in 63 patients with oral cavity cancers. In 37 (59%) patients with dental artifacts on CT/MRI, F-18-FDG PET/CT showed superior results compared to MRI in tumor staging and represented the highest intraclass correlation coefficient value to tumor volume determined by pathology. J. Surg. Oncol. 2014 110:696-701. (c) 2014 Wiley Periodicals, Inc. English WILEY NECK-CANCER HEAD TOMOGRAPHY VOLUME Clinical Values of F-18-FDG PET/CT in Oral Cavity Cancer with Dental Artifacts on CT or MRI Article 10.1002/jso.23691 1 JOURNAL OF SURGICAL ONCOLOGY, v.110, no.6, pp.696 - 701 JOURNAL OF SURGICAL ONCOLOGY 110 6 696 701 scie scopus 000343878300011 2-s2.0-84919578039 Oncology Surgery Oncology Surgery Article NECK-CANCER HEAD TOMOGRAPHY VOLUME oral cavity squamous cell carcinoma dental artifacts tumor volume magnetic resonance imaging F-18-FDG PET CT