Ryu, Ju Hee Lee, Sangmin Son, Sohee Kim, Sun Hwa Leary, James F. Choi, Kuiwon Kwon, Ick Chan 2024-01-20T09:00:53Z 2024-01-20T09:00:53Z 2021-09-02 2014-09-28 0168-3659 https://pubs.kist.re.kr/handle/201004/126330 The concept of personalized medicine has recently emerged as a promising way to address unmet medical needs. Due to the limitations of standard diagnostic and therapeutic strategies, the disease treatment is moving towards tailored treatment for individual patients, considering the inter-individual variability in therapeutic response. Theranostics, which involves the combination of therapy and diagnostic imaging into a single system, may fulfill the promise of personalized medicine. By integrating molecular imaging functionalities into therapy, theranostic approach could be advantageous in therapy selection, treatment planning, objective response monitoring and follow-up therapy planning based on the specific molecular characteristics of a disease. Although the field of therapy and imaging of its response have been independently developed thus far, developing imaging strategies can be fully exploited to revolutionize the theranostic systems in combination with the therapy modality. In this review, we describe the recent advances in molecular imaging technologies that have been specifically developed to evaluate the therapeutic efficacy for theranostic purposes. (C) 2014 Published by Elsevier B.V. English ELSEVIER SCIENCE BV PEGYLATED HYALURONIC-ACID DRUG-DELIVERY RHEUMATOID-ARTHRITIS MULTIFUNCTIONAL NANOPARTICLES TARGETED DELIVERY POLYMERIZED SIRNA CANCER DIAGNOSIS THERAPY THERAPEUTICS Theranostic nanoparticles for future personalized medicine Article 10.1016/j.jconrel.2014.04.027 1 JOURNAL OF CONTROLLED RELEASE, v.190, pp.477 - 484 JOURNAL OF CONTROLLED RELEASE 190 477 484 scie scopus 000345910900029 2-s2.0-84906787631 Chemistry, Multidisciplinary Pharmacology & Pharmacy Chemistry Pharmacology & Pharmacy Review PEGYLATED HYALURONIC-ACID DRUG-DELIVERY RHEUMATOID-ARTHRITIS MULTIFUNCTIONAL NANOPARTICLES TARGETED DELIVERY POLYMERIZED SIRNA CANCER DIAGNOSIS THERAPY THERAPEUTICS Theranostics Personalized medicine Molecular imaging Monitoring response