Choi, Ji Suk Choi, Young Chan Kim, Jae Dong Kim, Eun Ji Lee, Hee Young Kwon, Ick Chan Cho, Yong Woo 2024-01-20T09:01:45Z 2024-01-20T09:01:45Z 2022-01-25 2014-09 1598-5032 https://pubs.kist.re.kr/handle/201004/126374 Extracellular matrices (ECMs), isolated through decellularization of mammalian tissues, have been successfully used in a variety of tissue engineering and regenerative medicine applications. The composition and spatial structure of ECMs provide not only specific instructive cues for the growth, migration, and differentiation of various cells in vitro, but afford ideal substrates for in vivo tissue reconstruction. Adipose tissue, which is the most prevalent and expendable tissue in the body and can be harvested in large quantities with minimal morbidity, has received much attention as a rich source of ECMs. Recent studies have designed different processes to isolate intact ECMs from adipose tissue and have fabricated various three-dimensional (3-D) tissue engineering scaffolds such as microparticles, powders, sponges, sheets, and hydrogels for use in regenerative medicine, particularly for patients requiring soft tissue regeneration. Indeed, because of the abundance of ECM components within adipose tissue, combined with the relative ease of large tissue harvesting, adipose tissue is a valuable resource in tissue regeneration therapy, encompassing autotransplantation, allotransplantation, and xenotransplantion. We briefly review extraction and decellularization techniques of ECMs from adipose tissue, biological characterization and fabrication of ECM-based tissue engineering scaffolds, and their use in soft tissue engineering. English SPRINGER Adipose tissue: A valuable resource of biomaterials for soft tissue engineering Article 10.1007/s13233-014-2135-5 1 MACROMOLECULAR RESEARCH, v.22, no.9, pp.932 - 947 MACROMOLECULAR RESEARCH 22 9 932 947 N scie scopus kci ART001913954 000342414100003 2-s2.0-84918771518 Polymer Science Polymer Science Review BLADDER ACELLULAR MATRIX STEM-CELL SHAPE IN-VITRO REGENERATIVE MEDICINE MECHANICAL-PROPERTIES DECELLULARIZED MATRIX IMMUNE-RESPONSE DRUG-DELIVERY EXTRACELLULAR-MATRIX SCAFFOLDS SMALL-INTESTINE SUBMUCOSA adipose tissue extracellular matrix decellularization scaffold soft tissue engineering