Jung, Jae Hoon Roh, Jong-Lyel Lee, Jeong Hyun Kim, Sung-Bae Lee, Sang-wook Choi, Seung-Ho Nam, Soon Yuhl Kim, Sang Yoon 2024-01-20T10:32:21Z 2024-01-20T10:32:21Z 2021-09-05 2014-02 2212-4403 https://pubs.kist.re.kr/handle/201004/127154 Objective. This study examined prognostic factors in patients with head and neck squamous cell carcinoma with advanced neck disease. Study Design. The records of 191 patients with previously untreated head and neck squamous cell carcinoma and metastatic cervical lymph node (LN) >6 cm (cN, n = 70) and 3.01 to 6 cm (control, n = 121) in the greatest dimension were reviewed. Univariate and multivariate analyses were used to identify factors associated with disease-free survival (DFS) and locoregional control (LRC). Results. In the cN3 group, independent variables for DFS were age, active drinking, LN size, and extranodal extension (P < .05), and that for LRC was age (P = .025). In the control group, independent variables for DFS were tumor location and differentiation and LN bilaterality (P < .05), and that for LRC was LN bilaterality (P = .011). Conclusions. The survival of cN3 patients is affected by host and nodal characteristics including age, drinking, nodal size, and extranodal extension. English ELSEVIER SCIENCE INC NODE METASTASES CANCER N3 CHEMORADIOTHERAPY OUTCOMES CT DISSECTION VOLUME TNM US Prognostic factors in patients with head and neck squamous cell carcinoma with cN3 neck disease: a retrospective case-control study Article 10.1016/j.oooo.2013.09.010 1 ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, v.117, no.2, pp.178 - 185 ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY 117 2 178 185 scie scopus 000330023200022 2-s2.0-84892841740 Dentistry, Oral Surgery & Medicine Dentistry, Oral Surgery & Medicine Article NODE METASTASES CANCER N3 CHEMORADIOTHERAPY OUTCOMES CT DISSECTION VOLUME TNM US