Liu, Karen C. Yeo, Yoon 2024-01-20T10:34:17Z 2024-01-20T10:34:17Z 2022-01-25 2014-01 0253-6269 https://pubs.kist.re.kr/handle/201004/127250 Nanoparticulate (NP) drug carrier systems are attractive vehicles for selective drug delivery to solid tumors. Ideally, NPs should evade clearance by the reticuloendothelial system while maintaining the ability to interact with tumor cells and facilitate cellular uptake. Great effort has been made to fulfill these design criteria, yielding various types of functionalized NPs. Another important consideration in NP design is the physical and functional stability during circulation, which, if ignored, can significantly undermine the promise of intelligently designed NP drug carriers. This commentary reviews several NP examples with stability issues and their consequences, ending in a discussion of experimental methods for reliable prediction of NP stability. English PHARMACEUTICAL SOC KOREA Extracellular stability of nanoparticulate drug carriers Article 10.1007/s12272-013-0286-0 1 ARCHIVES OF PHARMACAL RESEARCH, v.37, no.1, pp.16 - 23 ARCHIVES OF PHARMACAL RESEARCH 37 1 16 23 N scie scopus kci 000329094700003 2-s2.0-84892935807 Chemistry, Medicinal Pharmacology & Pharmacy Pharmacology & Pharmacy Review POLYMERIC MICELLE BLOCK-COPOLYMER PHASE-I PACLITAXEL TUMOR CANCER PH DELIVERY ALBUMIN FORMULATION Nanomedicine Nanoparticles Drug delivery Stability Sensitivity