Ryu, In Sun Roh, Jong-Lyel Cho, Kyung-Ja Lee, Sang-Wook Choi, Seung-Ho Nam, Soon Yuhl Kim, Sang Yoon 2024-01-20T11:02:09Z 2024-01-20T11:02:09Z 2021-09-05 2013-12 1043-3074 https://pubs.kist.re.kr/handle/201004/127386 BackgroundWe compared clinical outcomes between patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesion and properly diagnosed as malignant lesion. MethodsThe outcomes were compared between patients with benign lesion and malignant lesion (44 each) on preoperative fine-needle aspiration cytology diagnosis who underwent conservative or radical surgery. ResultsFive-year lesion-free survival (DFS) rates were 86.8% for benign lesion and 76.3% for malignant lesion (p = .128). Surgical extent did not significantly affect locoregional recurrence and DFS (p = .360). Univariate analysis showed that sublingual gland tumor, positive resection margin, and extraparenchymal extension (EPE) were significantly associated with DFS (p < .05 each). On multivariate analysis, EPE remained an independent variable (p = .047, hazard ratio = 6.621, 95% confidence interval = 1.393-31.474). ConclusionsThe clinical outcomes of patients with salivary gland carcinomas misdiagnosed as benign are relatively favorable. Conservative surgery may be sufficient for patients with low-grade and T1-2 salivary gland carcinomas. (c) 2013 Wiley Periodicals, Inc. Head Neck 35: 1764-1770, 2013 English WILEY FINE-NEEDLE-ASPIRATION PRIMARY PAROTID CARCINOMA DIAGNOSTIC-ACCURACY PLEOMORPHIC ADENOMA FROZEN-SECTION TUMORS BIOPSY CYTOLOGY SURGERY PITFALLS Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions Article 10.1002/hed.23228 1 HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v.35, no.12, pp.1764 - 1770 HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 35 12 1764 1770 scie scopus 000327015500021 2-s2.0-84888004230 Otorhinolaryngology Surgery Otorhinolaryngology Surgery Article FINE-NEEDLE-ASPIRATION PRIMARY PAROTID CARCINOMA DIAGNOSTIC-ACCURACY PLEOMORPHIC ADENOMA FROZEN-SECTION TUMORS BIOPSY CYTOLOGY SURGERY PITFALLS salivary gland carcinomas preoperative cytology outcomes diagnosis recurrence