Heo, Seong-beom Jeon, Young-Sil Kim, Young Jun Kim, Soo Hyun Kim, Ji-Heung 2024-01-20T11:04:36Z 2024-01-20T11:04:36Z 2021-09-04 2013-11 1547-0091 https://pubs.kist.re.kr/handle/201004/127512 The catechol functional group of dopamine (3,4-dihydroxyphenethylamine) forms a strong coordinate bond with both inorganic and organic substrates in a wet environment. The nonfouling surfaces required for this process are typically prepared through the immobilization of poly(ethylene glycol), so-called, PEGylation. In this work, polyaspartamides containing adhesive catechol and methoxy PEG pendants were synthesized from polysuccinimide through successive aminolysis reactions. The adhesion and crosslinking of the polyaspartamide derivatives in pH-controlled aqueous media was successfully utilized to modify a glass surface using a simple immersion method. Contact angle, alpha-step profiler, SEM and EDS, XPS, and AFM were used to characterize and verify the surface coating. In addition, the biocompatibility and antifouling properties of the modified surface were elucidated with a cell viability test, and a protein adsorption experiment, respectively. This biocompatible polymer system has biomedical application potential for use in adhesives and the surface coating of various biomaterials. English SPRINGER PROTEIN ADSORPTION POLYETHYLENE-GLYCOL CROSS-LINKING AMPHIPHILIC POLYASPARTAMIDES BACTERIAL ADHESION MYTILUS-EDULIS CHAIN-LENGTH DERIVATIVES RESISTANCE OXIDE Bioinspired self-adhesive polymer for surface modification to improve antifouling property Article 10.1007/s11998-013-9528-9 1 JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH, v.10, no.6, pp.811 - 819 JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH 10 6 811 819 scie scopus 000325961300006 2-s2.0-84887214159 Chemistry, Applied Materials Science, Coatings & Films Chemistry Materials Science Article PROTEIN ADSORPTION POLYETHYLENE-GLYCOL CROSS-LINKING AMPHIPHILIC POLYASPARTAMIDES BACTERIAL ADHESION MYTILUS-EDULIS CHAIN-LENGTH DERIVATIVES RESISTANCE OXIDE Antifouling Dopamine Surface modification Polyaspartamide PEG