Stojanovic, Zoran Otonicar, Mojca Lee, Jongwook Stevanovic, Magdalena M. Hwang, Mintai P. Lee, Wan Hyi Choi, Jonghoon Uskokovic, Dragan 2024-01-20T11:32:54Z 2024-01-20T11:32:54Z 2021-09-04 2013-09-01 0927-7765 https://pubs.kist.re.kr/handle/201004/127677 We report a simple and green procedure for the preparation of magnetic iron oxide nanocrystals via solvothermal synthesis. The nanocrystal synthesis was carried out under mild conditions in the water-ethanol-oleic acid solvent system with the use of the oleate anion as a surface modifier of nanocrystals and glucose as a reducing agent. Specific conditions for homogenous precipitation achieved in such a reaction system lead to the formation of uniform high-quality nanocrystals down to 5 nm in diameter. The obtained hydrophobic nanocrystals can easily be converted to hydrophilic magnetic nanoparticles by being immobilized in a poly(L-lactide)-polyethyleneimine polymeric matrix. These hybrid nano-constructs may find various biomedical applications, such as magnetic separation, gene transfection and/or magnetic resonance imaging. (C) 2013 Elsevier B.V. All rights reserved. English ELSEVIER SCIENCE BV SIZE-CONTROLLED SYNTHESIS FE3O4 NANOPARTICLES SUPERPARAMAGNETIC NANOPARTICLES MONODISPERSE NANOCRYSTALS CONTRAST AGENTS SILICA MATRIX SEPARATION ROUTE MAGNETOFECTION TECHNOLOGY The solvothermal synthesis of magnetic iron oxide nanocrystals and the preparation of hybrid poly(L-lactide)-polyethyleneimine magnetic particles Article 10.1016/j.colsurfb.2013.03.053 1 COLLOIDS AND SURFACES B-BIOINTERFACES, v.109, pp.236 - 243 COLLOIDS AND SURFACES B-BIOINTERFACES 109 236 243 scie scopus 000320413300034 2-s2.0-84877355396 Biophysics Chemistry, Physical Materials Science, Biomaterials Biophysics Chemistry Materials Science Article SIZE-CONTROLLED SYNTHESIS FE3O4 NANOPARTICLES SUPERPARAMAGNETIC NANOPARTICLES MONODISPERSE NANOCRYSTALS CONTRAST AGENTS SILICA MATRIX SEPARATION ROUTE MAGNETOFECTION TECHNOLOGY Magnetic iron oxides Nanocrystals Solvothermal synthesis Surface functionalization Polyethyleneimine Poly(L-lactide)