Hasebe, Terumitsu Nagashima, So Kamijo, Aki Moon, Myoung-Woon Kashiwagi, Yousuke Hotta, Atsushi Lee, Kwang-Ryeol Takahashi, Koki Yamagami, Takuji Suzuki, Tetsuya 2024-01-20T11:33:45Z 2024-01-20T11:33:45Z 2021-09-05 2013-09 0925-9635 https://pubs.kist.re.kr/handle/201004/127720 We investigated the hydrophobicity and non-thrombogenicity of a nanoscale dual rough surface coated with hydrophobic and non-thrombogenic fluorine-incorporated diamond-like carbon (F-DLC) films. We prepared Si (1 0 0) and a dual rough surface composed of coarse posts and nano-sized fine posts as substrates. DLC film was deposited on the Si substrate, and F-DLC film was deposited on Si or the dual rough surface using radio frequency plasma enhanced chemical vapor deposition method. The surface hydrophobicity of each sample was examined with water contact angle measurements and the non-thrombogenicity was evaluated through incubation with platelet-rich plasma isolated from human whole blood. The water repellency was dramatically improved on the F-DLC-coated dual rough surface compared with that on DLC-coated Si or F-DLC-coated Si, which had a water contact angle of 130.6 degrees. There was no significant difference in the values for the platelet-covered area between DLC-coated Si and the F-DLC-coated dual rough surface. As DLC is being considered for widespread clinical use as a surface coating for medical devices owing to its non-thrombogenicity compared with other biomaterials, the F-DLC-coated dual rough surface presented in this study still has the potential for clinical use, such as temporary blood-contacting medical devices, to take advantage of its high hydrophobicity. (c) 2013 Elsevier B.V. All rights reserved. English ELSEVIER SCIENCE SA PLATELET-ADHESION PROTEIN ADSORPTION SUPERHYDROPHOBIC SURFACES ACTIVATION COATINGS DLC DEPOSITION TIN Hydrophobicity and non-thrombogenicity of nanoscale dual rough surface coated with fluorine-incorporated diamond-like carbon films: Biomimetic surface for blood-contacting medical devices Article 10.1016/j.diamond.2013.06.001 1 DIAMOND AND RELATED MATERIALS, v.38, pp.14 - 18 DIAMOND AND RELATED MATERIALS 38 14 18 scie scopus 000324664700003 2-s2.0-84879466950 Materials Science, Multidisciplinary Materials Science, Coatings & Films Physics, Applied Physics, Condensed Matter Materials Science Physics Article PLATELET-ADHESION PROTEIN ADSORPTION SUPERHYDROPHOBIC SURFACES ACTIVATION COATINGS DLC DEPOSITION TIN Nanoscale dual rough surface Diamond-like carbon Hydrophobicity Biomimetic surface Non-thrombogenicity