Hwang, Mintai P. Lee, Jong-Wook Lee, Kyung Eun Lee, Kwan Hyi 2024-01-20T11:33:53Z 2024-01-20T11:33:53Z 2021-09-04 2013-09 1936-0851 https://pubs.kist.re.kr/handle/201004/127727 The generation of nanosized probes often requires time-intensive and application-specific optimization processes that involve conjugating a nanoconstruct to a targeting moiety. Herein, we genetically modify apoferritin and generate a universal interface system composed of protein G and 6x His-tag. The resulting construct, conferred with modularity and high targeting efficiency, is applied toward two distinct applications in the detection of a pancreatic cancer biomarker and used to demonstrate its potential in the facile exchange of nanoprobe components. English AMER CHEMICAL SOC STREPTOCOCCAL PROTEIN-G QUANTUM DOTS CRYSTAL-STRUCTURE TAGGED PROTEINS FERRITIN GENES IGG-BINDING NANOPARTICLES FRAGMENT COMPLEX BIOMARKERS Think Modular: A Simple Apoferritin-Based Platform for the Multifaceted Detection of Pancreatic Cancer Article 10.1021/nn403465a 1 ACS NANO, v.7, no.9, pp.8167 - 8174 ACS NANO 7 9 8167 8174 scie scopus 000330016900078 2-s2.0-84884971237 Chemistry, Multidisciplinary Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Chemistry Science & Technology - Other Topics Materials Science Article STREPTOCOCCAL PROTEIN-G QUANTUM DOTS CRYSTAL-STRUCTURE TAGGED PROTEINS FERRITIN GENES IGG-BINDING NANOPARTICLES FRAGMENT COMPLEX BIOMARKERS apoferritin modular quantum dot gold nanoparticle pancreatic cancer