Cha, Pil-Ryung Han, Hyung-Seop Yang, Gui-Fu Kim, Yu-Chan Hong, Ki-Ha Lee, Seung-Cheol Jung, Jae-Young Ahn, Jae-Pyeong Kim, Young-Yul Cho, Sung-Youn Byun, Ji Young Lee, Kang-Sik Yang, Seok-Jo Seok, Hyun-Kwang 2024-01-20T11:35:02Z 2024-01-20T11:35:02Z 2021-09-04 2013-08-06 2045-2322 https://pubs.kist.re.kr/handle/201004/127781 Crystalline Mg-based alloys with a distinct reduction in hydrogen evolution were prepared through both electrochemical and microstructural engineering of the constituent phases. The addition of Zn to Mg-Ca alloy modified the corrosion potentials of two constituent phases (Mg + Mg2Ca), which prevented the formation of a galvanic circuit and achieved a comparable corrosion rate to high purity Mg. Furthermore, effective grain refinement induced by the extrusion allowed the achievement of much lower corrosion rate than high purity Mg. Animal studies confirmed the large reduction in hydrogen evolution and revealed good tissue compatibility with increased bone deposition around the newly developed Mg alloy implants. Thus, high strength Mg-Ca-Zn alloys with medically acceptable corrosion rate were developed and showed great potential for use in a new generation of biodegradable implants. English NATURE PUBLISHING GROUP MAGNESIUM CORROSION METALS IONS ZN TI Biodegradability engineering of biodegradable Mg alloys: Tailoring the electrochemical properties and microstructure of constituent phases Article 10.1038/srep02367 1 SCIENTIFIC REPORTS, v.3 SCIENTIFIC REPORTS 3 scie scopus 000322756500007 2-s2.0-84881472857 Multidisciplinary Sciences Science & Technology - Other Topics Article MAGNESIUM CORROSION METALS IONS ZN TI Biodegradable metal Magnesium alloy electrochemical properety microstructural engineering