Kim, Sang-Hoon Mun, Cho Hay Jung, Youngmee Kim, Sang-Heon Kim, Dong-Ik Kim, Soo Hyun 2024-01-20T12:00:45Z 2024-01-20T12:00:45Z 2021-09-05 2013-08 1598-5032 https://pubs.kist.re.kr/handle/201004/127811 We fabricated a tubular double-layered scaffold using two steps; poly(L-lactide-co-E >-caprolactone) (PLCL) gel spinning method and salt leaching. The objective of the present study was to characterize the mechanical properties of tubular double-layered PLCL scaffolds that had different wall thickness values. We evaluated the bio-vascular scaffold in terms of cardiovascular implants-tubular vascular prostheses in international standard; ANSI/AAMI/ISO 7198:1998/2001. According to the ISP 7198, PLCL had sufficient mechanical strength, burst strength, tensile strength to withstand blood pressure and had similar compliance to native vessels due to its elasticity. We applied the tubular vascular prostheses' evaluation method using an existing surgical operation. The vascular scaffold, which had a similar compliance to native vessels, did not result in severe thrombosis in vivo for 4 weeks. Thus, this novel material holds great promise for use as a blood vessel substitute. English SPRINGER COMPLIANCE MISMATCH TUBULAR SCAFFOLDS PLCL SCAFFOLDS TISSUE POLYCAPROLACTONE ARTERIES BEHAVIOR ELASTIN PATENCY FIBERS Mechanical properties of compliant double layered poly(L-lactide-co-epsilon-caprolactone) vascular graft Article 10.1007/s13233-013-1095-5 1 MACROMOLECULAR RESEARCH, v.21, no.8, pp.886 - 891 MACROMOLECULAR RESEARCH 21 8 886 891 scie scopus kci ART001798185 000319040000007 2-s2.0-84878219246 Polymer Science Polymer Science Article COMPLIANCE MISMATCH TUBULAR SCAFFOLDS PLCL SCAFFOLDS TISSUE POLYCAPROLACTONE ARTERIES BEHAVIOR ELASTIN PATENCY FIBERS poly(L-lactide-co-epsilon-caprolactone) gel-spinning molding technique double-layered scaffold dynamic compliance vascular tissue engineering