Kim, Miok Song, Na Rae Hong, Jongki Lee, Jeongae Pyo, Heesoo 2024-01-20T12:02:43Z 2024-01-20T12:02:43Z 2021-09-05 2013-07 0045-6535 https://pubs.kist.re.kr/handle/201004/127908 Persistent organochlorine pesticides (OCPs) are well known to accumulate in environment and to instigate disruptions in endocrine system. In the present study, 18 kinds of OCPs were bio-monitored from 1904 adult serums. Analysis was performed with headspace gas chromatography (HS-GC) which has the advantage to require small volume of serum (1 mL) without complex pretreatment and C-13 isotope labeled internal standard mix was used for quantitation. As a result, eleven out of 18 OCPs, including hexachlorobenzene (HCB) and dichlorodiphenyltrichloroethane metabolites (DDTs) were detected. HCB was the most frequently detected OCP (8.0%) with an average concentration of 1.74 ng g(-1), lipid (2.10 ng g(-1), lipid-99.80 ng g(-1), lipid). p,p'-Dichlorodiphenyldichloroethylene (p,p'-DDE) had the highest average concentration of 21.65 ng g(-1), lipid (12.80 ng g(-1), lipid-2270 ng g(-1) lipid) and was detected from 7.5% of serum samples. The average concentration of Sigma DDT metabolites was 32.04 ng g(-1) lipid (6.61 ng g(-1) lipid-2800 ng g(-1) lipid) with detection frequency of 9.0%. Results interpreted with respect to age groups showed increase in Sigma OCPs and Sigma DDTs concentrations as age increases, except for the 20. Results interpreted with respect to gender, in general, illustrated higher detected concentration of OCPs in male serums than in female serums; however, the result trend was reversed in age group of the sixties. The above results will be applicable to health impact assessment of Koreans in relation to environmental contaminations. Published by Elsevier Ltd. English PERGAMON-ELSEVIER SCIENCE LTD POLYCHLORINATED-BIPHENYLS HUMAN-MILK EXPOSURE PCBS OCPS AGE ASSOCIATION GENDER WOMEN DDT Quantitative analysis of organochlorine pesticides in human serum using headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry Article 10.1016/j.chemosphere.2013.02.052 1 CHEMOSPHERE, v.92, no.3, pp.279 - 285 CHEMOSPHERE 92 3 279 285 scie scopus 000320220600006 2-s2.0-84877715825 Environmental Sciences Environmental Sciences & Ecology Article POLYCHLORINATED-BIPHENYLS HUMAN-MILK EXPOSURE PCBS OCPS AGE ASSOCIATION GENDER WOMEN DDT Organochlorine pesticides HS-SPME GC-MS Human serum