Khan, Mohammad Ashrafuddin El-Gamal, Mohammed I. Oh, Chang-Hyun 2024-01-20T12:03:34Z 2024-01-20T12:03:34Z 2022-01-10 2013-06-20 0253-2964 https://pubs.kist.re.kr/handle/201004/127949 6,7-Dimethoxy-2-methyl-3-(4-nitrophenoxy)quinoline was synthesized by Friedlander's cyclization reaction. Different bases and solvents were tested in order to optimize the reaction conditions. The highest yields were obtained using piperidine in refluxing ethanol. Further reactions were carried out in order to prepare different diarylamide and diarylurea derivatives in moderate to high yields in order to examine their anticancer activities. English KOREAN CHEMICAL SOC QUINOLINES Optimization of the Reaction Conditions for Synthesis of 3-(Aryloxy)quinoline Derivatives via Friedlander's Cyclization Reaction Article 10.5012/bkcs.2013.34.6.1848 1 BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.34, no.6, pp.1848 - 1852 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 34 6 1848 1852 scie scopus kci ART001775332 000321234300042 2-s2.0-84879212882 Chemistry, Multidisciplinary Chemistry Article QUINOLINES Cyclization reaction 2-Amino-4,5-dimethoxybenzaldehyde Friedlander&apos s reaction Quinoline