Ban, Eunmi Song, Eun Joo 2024-01-20T12:03:44Z 2024-01-20T12:03:44Z 2021-09-05 2013-06-15 1570-0232 https://pubs.kist.re.kr/handle/201004/127958 Since the human genomic project, the analysis of biomolecules using biotechnology and biopharmaceuticals has become increasingly important for the investigation of molecular mechanisms of biological processes and disease, as well as for the discovery of new biomarkers and drug targets. Among a number of analytical tools and technologies, capillary electrophoresis (CE) is emerging as a useful analytical tool for analyzing various biomolecules, as well as for performing genome sequencing in biological studies because of the simple sample preparation involved in the method and the efficient resolution of compounds of various sizes. In particular, CE with laser-induced fluorescence (CE-LIF) detection is a promising and relatively rapidly developing tool with the potential to provide a highly sensitive and specific analysis of biological molecules. This paper gives a short overview of the methodological and instrumental developments and applications of microchip-based CE and CE-LIF for the analysis of DNA, RNA, proteins, and peptides in the past 3 years (C) 2013 Elsevier B.V. All rights reserved. English ELSEVIER SQUARYLIUM CYANINE DYE CE-LIF GEL-ELECTROPHORESIS MICROCHIP ELECTROPHORESIS SIEVING ELECTROPHORESIS QUANTITATIVE-ANALYSIS ZONE-ELECTROPHORESIS MICRORNA DETECTION MASS DETECTION BORONIC ACID Recent developments and applications of capillary electrophoresis with laser-induced fluorescence detection in biological samples Article 10.1016/j.jchromb.2013.04.028 1 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, v.929, pp.180 - 186 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 929 180 186 scie scopus 000320085300026 2-s2.0-84878218184 Biochemical Research Methods Chemistry, Analytical Biochemistry & Molecular Biology Chemistry Review SQUARYLIUM CYANINE DYE CE-LIF GEL-ELECTROPHORESIS MICROCHIP ELECTROPHORESIS SIEVING ELECTROPHORESIS QUANTITATIVE-ANALYSIS ZONE-ELECTROPHORESIS MICRORNA DETECTION MASS DETECTION BORONIC ACID Capillary electrophoresis Laser-induced fluorescence Biomolecules