Hoang, Hoa Thi Lee, Taemin Kim, Byeong-Su Han, Ki-Cheol Ahn, Dae-Ro 2024-01-20T12:30:54Z 2024-01-20T12:30:54Z 2021-09-05 2013-05-01 0960-894X https://pubs.kist.re.kr/handle/201004/128071 Immunoassay is an important technique to detect the disease biomarkers and pathogenic biological agents which often present at low levels in clinical samples. To improve sensitivity of the immunoassay, here we described the DNA-coated, nano-sized micelles in which the DNA strands play a role as signal generators in an immunoassay. This micelle-based immunoassay was evaluated for quantitation of a liver cancer biomarker and the sensitivity of the method was compared with those of the conventional methods. (C) 2013 Elsevier Ltd. All rights reserved. English Pergamon Press Ltd. IMMUNOSORBENT-ASSAY WATER ELISA ACID An immunoassay utilizing the DNA-coated polydiacetylene micelles as a signal generator Article 10.1016/j.bmcl.2013.02.087 1 Bioorganic & Medicinal Chemistry Letters, v.23, no.9, pp.2675 - 2678 Bioorganic & Medicinal Chemistry Letters 23 9 2675 2678 scie scopus 000317333900039 2-s2.0-84876099069 Chemistry, Medicinal Chemistry, Organic Pharmacology & Pharmacy Chemistry Article IMMUNOSORBENT-ASSAY WATER ELISA ACID Polydiacetylene (PDA) Micelles Immunoassay Fluorescence intensity Alpha-fetoprotein (AFP)