Mallick, Sudipta Sun, In-Cheol Kim, Kwangmeyung Yi, Dong Kee 2024-01-20T12:31:16Z 2024-01-20T12:31:16Z 2021-09-05 2013-05 1533-4880 https://pubs.kist.re.kr/handle/201004/128089 Due to their efficient conversion of absorbed light energy to heat gold nanorods have been proved to be an amazing tool for minimally invasive photo-thermal cancer therapy. The present in vitro study demonstrates the ability of silica coated Au nanorods to function as a dual probe for cancer-cell therapy and imaging without any toxic side-effects. HeLa cells were incubated with silica coated Au nanorods and imaged inside the cell just after 1 hour of incubation by a dark field set up due to strong surface enhanced Raman scattering. To induce hyperthermia, silica coated Au nanorod incubated HeLa cells were illuminated with a diode laser (671 nm, 200 mW, 10 min). Cell destruction was observed even at a very low dose of nanorods, whereas none was observed in the absence of nanorods. Silica coated Au nanorods thus offer a promising, novel class of selective photo-thermal agents for cancer therapy and diagnosis. English AMER SCIENTIFIC PUBLISHERS OPTICAL-PROPERTIES CONTRAST AGENTS AU NANORODS NANOPARTICLES SCATTERING ABSORPTION ANTIBODIES CARCINOMA PROBE SIZE Silica Coated Gold Nanorods for Imaging and Photo-Thermal Therapy of Cancer Cells Article 10.1166/jnn.2013.7149 1 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.13, no.5, pp.3223 - 3229 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 13 5 3223 3229 scie scopus 000319953300007 2-s2.0-84876922624 Chemistry, Multidisciplinary Nanoscience & Nanotechnology Materials Science, Multidisciplinary Physics, Applied Physics, Condensed Matter Chemistry Science & Technology - Other Topics Materials Science Physics Article OPTICAL-PROPERTIES CONTRAST AGENTS AU NANORODS NANOPARTICLES SCATTERING ABSORPTION ANTIBODIES CARCINOMA PROBE SIZE Au-Nanorods Surface Functionalization Photo-Thermal Therapy