Cho, Young-Wook Roh, Jong-Lyel Jung, Jae Hoon Kim, Sung-Bae Lee, Sang-wook Choi, Seung-Ho Nam, Soon Yuhl Kim, Sang Yoon Kim, Sang Yoon 2024-01-20T12:32:46Z 2024-01-20T12:32:46Z 2022-01-10 2013-04-01 0163-5581 https://pubs.kist.re.kr/handle/201004/128163 Significant loss of body weight (SLW) by patients treated for squamous cell carcinomas of the oral cavity and oropharynx (OSCC) may affect treatment completion and results. We assessed factors predicting SLW and its correlation with disease-free survival (DFS) in these patients. We evaluated 226 consecutive patients with previously untreated, operable OSCC whose body weight was recorded before, during, and for up to 1 year after treatment. SLW was defined as 10% reduction in pretreatment body weight. Clinicopathologic parameters were compared in patients with and without SLW. Of the 226 patients, 94 (41.6%) experienced SLW and 132 (58.4%) did not. Univariate analyses showed that factors significantly associated with SLW included T34, N+, stage IIIIV, and oropharyngeal tumors, nonsurgical (radiotherapy or chemotherapy) vs. surgical treatment, posttreatment recurrence, histologic differentiation, involved resection margin, and number of metastatic lymph nodes (pLNs) 3 (P < 0.05). Multivariate analyses showed that radiotherapy, recurrence, and number of pLNs were significant independent predictors of SLW (P < 0.005). DFS rate was significantly higher in patients without than with SLW (P < 0.01). OSCC patients with multiple pLNs, those undergoing radiotherapy, and those with posttreatment recurrences may require close nutritional monitoring and support. English ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD QUALITY-OF-LIFE LOCALLY ADVANCED HEAD ENDOSCOPIC GASTROSTOMY TUBE NECK-CANCER PATIENTS DEFINITIVE RADIOTHERAPY CONTROLLED-TRIAL CHEMORADIATION DYSPHAGIA NUTRITION RADIATION Prediction of Posttreament Significant Body Weight Loss and Its Correlation with Disease-Free Survival in Patients with Oral Squamous Cell Carcinomas Article 10.1080/01635581.2013.767365 1 NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, v.65, no.3, pp.417 - 423 NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL 65 3 417 423 scie scopus 000316655700011 2-s2.0-84876135659 Oncology Nutrition & Dietetics Oncology Nutrition & Dietetics Article QUALITY-OF-LIFE LOCALLY ADVANCED HEAD ENDOSCOPIC GASTROSTOMY TUBE NECK-CANCER PATIENTS DEFINITIVE RADIOTHERAPY CONTROLLED-TRIAL CHEMORADIATION DYSPHAGIA NUTRITION RADIATION