Lee, Ji-Young Kim, Seungki Lee, Jong-Tae Choi, Jong-Ho Lee, Jeongae Pyo, Heesoo 2024-01-20T13:30:25Z 2024-01-20T13:30:25Z 2021-09-05 2012-12-20 0253-2964 https://pubs.kist.re.kr/handle/201004/128536 Headspace (HS) and headspace solid-phase microextraction (HS-SPME) were studied for extracting volatile organic compounds (VOCs) from whole blood, with chemical and instrumental variables being optimized for maximum sensitivity: incubation at 60 degrees C, equilibration for 30 mm, pH 11, and 2 mL injection volume. Both techniques provided accurate analyses, with detection limits of 0.05-0.1 ng mL(-1) and 0.05-0.5 ng mL(-1). HS showed better sensitivity, reproducibility, and analysis times than HS-SPME. Overall levels of chloroform in whole blood were found to be 0.05-5.84 ng mL(-1); detected levels of benzene were 0.05-2.20 ng mL(-1). English KOREAN CHEMICAL SOC SOLID-PHASE MICROEXTRACTION WATER HYDROCARBONS OPTIMIZATION CONTAMINANTS PESTICIDES TOXICITY BENZENE TOLUENE SOILS Rapid Determination of Volatile Organic Compounds in Human Whole Blood Using Static Headspace Sampling with Gas Chromatography and Mass Spectrometry Article 10.5012/bkcs.2012.33.12.3963 1 BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.33, no.12, pp.3963 - 3970 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 33 12 3963 3970 scie scopus kci ART001718723 000313154400010 2-s2.0-84871769259 Chemistry, Multidisciplinary Chemistry Article SOLID-PHASE MICROEXTRACTION WATER HYDROCARBONS OPTIMIZATION CONTAMINANTS PESTICIDES TOXICITY BENZENE TOLUENE SOILS VOCs Whole blood Headspace HS-GC-MS