Park, Gi Cheol Cho, Kyung-Ja Kang, Jun Roh, Jong-Lyel Choi, Seung-Ho Kim, Sang Yoon Nam, Soon Yuhl 2024-01-20T13:31:34Z 2024-01-20T13:31:34Z 2021-09-05 2012-12 0022-4790 https://pubs.kist.re.kr/handle/201004/128595 Background This study evaluated the relationships between capsular characteristics and recurrence of parotid pleomorphic adenomas. Methods The pathological slides and clinical data of 110 patients that underwent superficial parotidectomy for pleomorphic adenoma in the parotid gland were reviewed retrospectively. The recurrent and non-recurrent groups comprised 10 and 100 patients, respectively. The two groups were compared with regard to their clinicopathological features, including the capsular characteristics. Results Satellite nodules were observed in six of the 10 recurrent group patients (60.0%) but in only 10 of the 100 non-recurrent group patients (10.0%) (P?=?0.001). Five of the recurrent group subjects (50%), but only 11 of the 100 non-recurrent group subjects (11.0%), had positive resection margins (P?=?0.006). Perioperative rupture of the tumor was observed in three recurrent group subjects (30%), but in only four of the non-recurrent group subjects (4.0%) (P?=?0.016). Multivariate analyses showed that the risk of recurrence was more than fivefold higher when satellite nodules were present (P?=?0.010) and more than 14-fold higher when the tumor had ruptured (P?=?0.001). Conclusions Satellite nodules and tumor rupture increase the risk of recurrence in patients with pleomorphic adenomas treated by superficial parotidectomy. J. Surg. Oncol. 2012; 106: 942946. (c) 2012 Wiley Periodicals, Inc. English WILEY-BLACKWELL TERM-FOLLOW-UP SALIVARY-GLANDS MIXED TUMORS CLASSIFICATION EXPERIENCE Relationship between histopathology of pleomorphic adenoma in the parotid gland and recurrence after superficial parotidectomy Article 10.1002/jso.23202 1 JOURNAL OF SURGICAL ONCOLOGY, v.106, no.8, pp.942 - 946 JOURNAL OF SURGICAL ONCOLOGY 106 8 942 946 scie scopus 000311109800004 2-s2.0-84869509760 Oncology Surgery Oncology Surgery Article TERM-FOLLOW-UP SALIVARY-GLANDS MIXED TUMORS CLASSIFICATION EXPERIENCE histopathology recurrence pleomorphic adenoma capsule parotid gland