Mun, Cho Hay Jung, Youngmee Kim, Sang-Heon Lee, Sun-Hee Kim, Hee Chan Kwon, Il Keun Kim, Soo Hyun 2024-01-20T14:05:01Z 2024-01-20T14:05:01Z 2021-09-05 2012-08 1937-3341 https://pubs.kist.re.kr/handle/201004/129014 Nanofibers have been applied to tissue engineering scaffolds because fiber diameters are of the same scale as the physical structure of protein fibrils in the native extracellular matrix. In this study, we utilized cell matrix engineering combined with cell sheet matrix and electrospinning technologies. We studied small-diameter vascular grafts in vitro by seeding smooth muscle cells onto electrospun poly(lactide-co-epsilon-caprolactone) (PLCL) scaffolds, culturing and constructing a three-dimensional network. The vascular grafts constructed using cell matrix engineering were similar to the native vessels in their mechanical properties, such as tensile strength, tensile strain, and e-modulus. Also, they had a self-sealing property more improved than GORE-TEX because PLCL has compatible elasticity. Small-diameter vascular grafts constructed using matrix engineering have the potential to be suitable for vascular grafts. English MARY ANN LIEBERT, INC MESENCHYMAL STEM-CELLS AMERICAN-HEART-ASSOCIATION MECHANICAL-PROPERTIES BLOOD-VESSELS IN-VITRO SCAFFOLDS FABRICATION MANAGEMENT PROPERTY DISEASE Three-Dimensional Electrospun Poly(Lactide-Co-epsilon-Caprolactone) for Small-Diameter Vascular Grafts Article 10.1089/ten.tea.2011.0695 1 TISSUE ENGINEERING PART A, v.18, no.15-16, pp.1608 - 1616 TISSUE ENGINEERING PART A 18 15-16 1608 1616 scie scopus 000307999100008 2-s2.0-84865207552 Cell & Tissue Engineering Cell Biology Engineering, Biomedical Materials Science, Biomaterials Cell Biology Engineering Materials Science Article MESENCHYMAL STEM-CELLS AMERICAN-HEART-ASSOCIATION MECHANICAL-PROPERTIES BLOOD-VESSELS IN-VITRO SCAFFOLDS FABRICATION MANAGEMENT PROPERTY DISEASE