Cho, Sung Youn Chae, Soo-Won Choi, Kui Won Seok, Hyun Kwang Han, Hyung Seop Yang, Seok Jo Kim, Young Yul Kim, Jong Tac Jung, Jae Young Assad, Michel 2024-01-20T14:05:10Z 2024-01-20T14:05:10Z 2021-09-05 2012-08 1552-4973 https://pubs.kist.re.kr/handle/201004/129022 In this study, a newly developed Mg-Ca-Zn alloy for low degradation rate and surface erosion properties was evaluated. The compressive, tensile, and fatigue strength were measured before implantation. The degradation behavior was evaluated by analyzing the microstructure and local hardness of the explanted specimen. Mean and maximum degradation rates were measured using micro CT equipment from 4-, 8-, and 16- week explants, and the alloy was shown to display surface erosion properties. Based on these characteristics, the average and minimum load bearing capacities in tension, compression, and bending modes were calculated. According to the degradation rate and references of recommended dietary intakes (RDI), the Mg-Ca-Zn alloy appears to be safe for human use. (c) 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 100B: 15351544, 2012. English WILEY-BLACKWELL MAGNESIUM ALLOYS PURE MAGNESIUM BONE BIOMATERIALS CORROSION SCAFFOLDS POLYMERS IMPLANTS DEVICES Load-bearing capacity and biological allowable limit of biodegradable metal based on degradation rate in vivo Article 10.1002/jbm.b.32722 1 JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, v.100B, no.6, pp.1535 - 1544 JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 100B 6 1535 1544 scie scopus 000305972800010 2-s2.0-84863724194 Engineering, Biomedical Materials Science, Biomaterials Engineering Materials Science Article MAGNESIUM ALLOYS PURE MAGNESIUM BONE BIOMATERIALS CORROSION SCAFFOLDS POLYMERS IMPLANTS DEVICES load bearing biodegradable alloy magnesium degradation rate implant