Kim, Sang Min Jeon, Je-Seung Kang, Suk Woo Jung, Yu-Jin Ly, Lin Na Um, Byung-Hun 2024-01-20T14:32:54Z 2024-01-20T14:32:54Z 2021-09-05 2012-06-06 0021-8561 https://pubs.kist.re.kr/handle/201004/129151 Ligularia fischeri (Ledeb.) Turcz, a commercial leafy vegetable, contains caffeoylquinic acid derivatives (CQAs) as major phenolic constituents. The HPLC chromatograms of leaf extracts collected from different areas in Korea showed a significant variation in CQA amount, and two tri-O-caffeoylquinic acids (triCQAs) were purified and structurally identified by NMR and MS from this plant. Radical scavenging activities among CQAs were found to be increased in proportion to the number of caffeoyl groups. Since this plant prefers damp and shady growth conditions, the effects of sunlight were investigated by growing plantlets in sunlight and shade for four weeks. Greater leaf thickness and higher phenolic contents were found for leaves grown in sunlight than in shade. Four major CQAs-5-mono-O-caffeoylquinic acid (5-monoCQA), and 3,4-, 3,5-, and 4,5-di-O-caffeoylquinic acid (diCQA)-were induced by solar irradiation, whereas the content of these compounds decreased steadily in shade leaves. The leaves of L. fischeri clearly showed adaptation responses to sunlight, and these characteristics can be exploited for cultivation of this plant for potential use as a nutraceutical and functional food. English AMER CHEMICAL SOC DICAFFEOYLQUINIC ACIDS OXIDATIVE STRESS VAR. SPICIFORMIS IDENTIFICATION ISOMERS EXTRACT ONLINE LEAVES Content of Antioxidative Caffeoylquinic Acid Derivatives in Field-Grown Ligularia fischeri (Ledeb.) Turcz and Responses to Sunlight Article 10.1021/jf300976y 1 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.60, no.22, pp.5597 - 5603 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 60 22 5597 5603 scie scopus 000304837700012 Agriculture, Multidisciplinary Chemistry, Applied Food Science & Technology Agriculture Chemistry Food Science & Technology Article DICAFFEOYLQUINIC ACIDS OXIDATIVE STRESS VAR. SPICIFORMIS IDENTIFICATION ISOMERS EXTRACT ONLINE LEAVES adaptation caffeoylquinic acid chlorophylls Ligularia fischeri phenolic compound radical scavenging activity