Chu, Jun-Uk Song, Kang-Il Han, Sungmin Lee, Soo Hyun Kim, Jinseok Kang, Ji Yoon Hwang, Dosik Suh, Jun-Kyo Francis Choi, Kuiwon Youn, Inchan 2024-01-20T14:34:18Z 2024-01-20T14:34:18Z 2021-09-04 2012-06 0967-3334 https://pubs.kist.re.kr/handle/201004/129223 Cuff electrodes are effective for chronic electroneurogram (ENG) recording while minimizing nerve damage. However, the ENG signals are usually contaminated by electromyogram (EMG) activity from the surrounding muscles, stimulus artifacts produced by the electrical stimulation and noise generated in the first stage of the neural signal amplifier. This paper proposed a new cuff electrode to reduce the interference from EMG signals and stimulus artifacts. As a result, when an additional middle electrode was placed at the center of the cuff electrode, a significant improvement in the signal-to-interference ratio was achieved at 11% for the EMG signals and 12% for the stimulus artifacts when compared to a conventional tripolar cuff. Furthermore, a new low-noise amplifier was proposed to improve the signal-to-noise ratio. The circuit was designed based on a noise analysis to minimize the noise, and the results show that the total noise of the amplifier was below 1 mu V for a cuff impedance of 1 k Omega and a frequency bandwidth of 300 to 5000 Hz. English IOP PUBLISHING LTD ACTION-POTENTIALS RECORDINGS PERFORMANCE REDUCTION AMPLIFIER Improvement of signal-to-interference ratio and signal-to-noise ratio in nerve cuff electrode systems Article 10.1088/0967-3334/33/6/943 1 PHYSIOLOGICAL MEASUREMENT, v.33, no.6, pp.943 - 967 PHYSIOLOGICAL MEASUREMENT 33 6 943 967 scie scopus 000304562900006 2-s2.0-84861148659 Biophysics Engineering, Biomedical Physiology Biophysics Engineering Physiology Article ACTION-POTENTIALS RECORDINGS PERFORMANCE REDUCTION AMPLIFIER cuff electrode peripheral nerve revised quasi-tripole configuration low-noise amplifier