Lee, Dong-Eun Kim, Ah Young Yoon, Hong Yeol Choi, Ki Young Kwon, Ick Chan Jeong, Seo Young Park, Jae Hyung Kim, Kwangmeyung 2024-01-20T14:34:26Z 2024-01-20T14:34:26Z 2021-09-04 2012-06 0959-9428 https://pubs.kist.re.kr/handle/201004/129230 The amphiphilic hyaluronic acid-5 beta-cholanic acid (HA-CA) conjugates were synthesized to fabricate near-infrared fluorescence (NIRF) dye conjugated and water-dispersible SPION-encapsulated hyaluronic acid nanoparticles (HNPs) for a tumor-targeted optical and magnetic resonance (MR) dual imaging contrast agent. Notably, HNPs were preferentially accumulated in the tumor region, implying that the hydrophilic HA shells of nanoparticles allow prolonged circulation and excellent active targeting of the SPION encapsulated nanoparticles in tumor-bearing mice. English ROYAL SOC CHEMISTRY CANCER-THERAPY PACLITAXEL CD44 MRI Amphiphilic hyaluronic acid-based nanoparticles for tumor-specific optical/MR dual imaging Article 10.1039/c2jm31406a 1 JOURNAL OF MATERIALS CHEMISTRY, v.22, no.21, pp.10444 - 10447 JOURNAL OF MATERIALS CHEMISTRY 22 21 10444 10447 scie scopus 000303816200007 2-s2.0-84862670555 Chemistry, Physical Materials Science, Multidisciplinary Chemistry Materials Science Article CANCER-THERAPY PACLITAXEL CD44 MRI