Bae, Soon Eon Park, Kwideok Han, Dong Keun 2024-01-20T16:32:51Z 2024-01-20T16:32:51Z 2021-09-05 2011-08 1738-2696 https://pubs.kist.re.kr/handle/201004/130109 Titanium (Ti) and its alloys were frequently used in many surgical and dental implants because of its good biocompatibility and mechanical properties. However, they often lack a direct bonding with bone after implantation. In order to enhance a new bone formation, surface composition and roughness of metal implants need to be carefully controlled. In this study, Ti implant discs were modified by using two oxidative methods; chemical (NH4OH/H2O2/H2O) and physical (O-2 plasma) treatments. Hydroxyapatite (HA) deposition on the surface of oxidative Ti samples was then induced in simulated body fluid (SBF) for 7 days in vitro. When the surface morphology of HA-formed Ti was determined using SEM, the surface layer was covered with nano-scaled HA particles. The chemically treated HA-Ti specimens provided preosteoblast with more favorable surface environment in up-regulating cell proliferation and alkaline phosphatase (ALP) activity. The present data indicated that the surface treatment of Ti could have a significant impact on HA formation, preosteoblast proliferation, and differentiation. Korean KOREAN TISSUE ENGINEERING REGENERATIVE MEDICINE SOC CALCIUM-PHOSPHATE COATINGS OSSEOINTEGRATION IMPLANTS ALLOY Characteristics and Cell Adhesion on Hydroxyapatite-Formed Titanium by Surface Modification Article 1 TISSUE ENGINEERING AND REGENERATIVE MEDICINE, v.8, no.4, pp.116 - 122 TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8 4 116 122 scie scopus kci other ART001574558 000293490400019 2-s2.0-84884557080 Cell & Tissue Engineering Engineering, Biomedical Cell Biology Engineering Article CALCIUM-PHOSPHATE COATINGS OSSEOINTEGRATION IMPLANTS ALLOY titanium dental implants oxidative treatment hydroxyapatite preosteoblast