Kim, Min Cheol Kwon, Hak Cheol Kim, Su Nam Kim, Hyung Seop Um, Byung Hun 2024-01-20T16:35:11Z 2024-01-20T16:35:11Z 2021-09-05 2011-07 0009-2363 https://pubs.kist.re.kr/handle/201004/130225 Four new plastoquinones, together with two known compounds, sargahydroquinoic acid and sargaquinoic acid, were isolated from the brown alga, Sargassum yezoense collected from the eastern coast of Korea. The structures of these compounds were elucidated based on spectroscopic analyses including NMR and MS. Their structures designated as meroterphenol A (1), B (2), C (3) and D (4) were characterized by a 6-methyl-1,4-benzohydroquinone moiety with an oxygenated diterpenoic acid chain. Meroterphenols A-D showed potent activation effects on peroxisome proliferator-activated receptor gamma (PPAR gamma). English PHARMACEUTICAL SOC JAPAN MARINE NATURAL-PRODUCTS BROWN-ALGA THIAZOLIDINEDIONE BINDING TORTILE DISEASE PPARS DNA Plastoquinones from Sargassum yezoense; Chemical Structures and Effects on the Activation of Peroxisome Proliferator-Activated Receptor Gamma Article 10.1248/cpb.59.834 1 CHEMICAL & PHARMACEUTICAL BULLETIN, v.59, no.7, pp.834 - 838 CHEMICAL & PHARMACEUTICAL BULLETIN 59 7 834 838 scie scopus 000292344000002 2-s2.0-79959789098 Chemistry, Medicinal Chemistry, Multidisciplinary Pharmacology & Pharmacy Pharmacology & Pharmacy Chemistry Article MARINE NATURAL-PRODUCTS BROWN-ALGA THIAZOLIDINEDIONE BINDING TORTILE DISEASE PPARS DNA Smgassum yezoense plastozuinone peroxisome proliferator-activated receptor gamma agonist Brown algae Sargassacea