Ham, Jungyeob Chin, Jungwook Kang, Heonjoong 2024-01-20T17:03:18Z 2024-01-20T17:03:18Z 2021-09-02 2011-05 1420-3049 https://pubs.kist.re.kr/handle/201004/130383 We have successfully prepared E-guggulsterone from 16,17-epoxypregnenolone in 84% yield over two steps via a hydrazine reduction and Oppenhauer oxidation. Additionally, isomerization was induced by heat, light (h nu) and acid catalysis to convert E-guggulsterone into the corresponding Z isomer. English MDPI AG COMMIPHORA-MUKUL STEREOCHEMISTRY KINASE CELLS A Regioselective Synthesis of E-Guggulsterone Article 10.3390/molecules16054165 1 MOLECULES, v.16, no.5, pp.4165 - 4171 MOLECULES 16 5 4165 4171 scie scopus 000290955800051 2-s2.0-79957614233 Biochemistry & Molecular Biology Chemistry, Multidisciplinary Biochemistry & Molecular Biology Chemistry Article COMMIPHORA-MUKUL STEREOCHEMISTRY KINASE CELLS guggulsterone inflammatory bowel diseases regioselective synthesis oppenhauer oxidation