Mancuso, James J. Kim, Jinsook Lee, Soojung Tsuda, Sachiko Chow, Nicholas B. H. Augustine, George J. 2024-01-20T18:00:32Z 2024-01-20T18:00:32Z 2022-01-10 2011-01-01 0958-0670 https://pubs.kist.re.kr/handle/201004/130737 Recently developed optogenetic technologies offer the promise of high-speed mapping of brain circuitry. Genetically targeted light-gated channels and pumps, such as channelrhodopsins and halorhodopsin, allow optical control of neuronal activity with high spatial and temporal resolution. Optogenetic probes of neuronal activity, such as Clomeleon and Mermaid, allow light to be used to monitor the activity of a genetically defined population of neurons. Combining these two complementary sets of optogenetic probes will make it possible to perform all-optical circuit mapping. Owing to the improved efficiency and higher speed of data acquisition, this hybrid approach should enable high-throughput mapping of brain circuitry. English WILEY IMAGING SYNAPTIC INHIBITION GREEN FLUORESCENT PROTEINS NEURAL CIRCUITRY TRANSGENIC MICE CHLORIDE INDICATOR OPTICAL CONTROL SENSITIVE DYES IN-VIVO CHANNEL VOLTAGE Optogenetic probing of functional brain circuitry Article 10.1113/expphysiol.2010.055731 1 EXPERIMENTAL PHYSIOLOGY, v.96, no.1, pp.26 - 33 EXPERIMENTAL PHYSIOLOGY 96 1 26 33 scie scopus 000285356800005 2-s2.0-78650122245 Physiology Physiology Review IMAGING SYNAPTIC INHIBITION GREEN FLUORESCENT PROTEINS NEURAL CIRCUITRY TRANSGENIC MICE CHLORIDE INDICATOR OPTICAL CONTROL SENSITIVE DYES IN-VIVO CHANNEL VOLTAGE