Pan, C.-H. Lee, J.Y. Song, D.-G. Kim, J.H. Ahn, S.Y. Bae, D.S. Kim, Y.H. Lee, J.K. 2024-01-20T20:30:19Z 2024-01-20T20:30:19Z 2021-09-02 2009-12 1976-0442 https://pubs.kist.re.kr/handle/201004/131949 Aldo-keto reductase family 1 B10 (AKR1B10) has been considered as a potential cancer therapeutic target. Ethanol extracts prepared from 82 Korean local plants were examined for their antioxidant activity and inhibitory effects on recombinant human AKR1B10 (rhAKR1B10) in vitro. 21 extracts showed more than 80% of ABTS radical scavenging activity at 100 μg/mL and 11 extracts inhibited more than 50% of rhAKR1B10 activity at 10 μg/mL. Especially, 9 extracts showed potent inhibition on rhAKR1B10 activity compared with positive control tetramethylene glutaric acid. English Antioxidant and Aldo-keto reductase family 1 B10 inhibition activities of korean local plant extracts Article 10.3839/jabc.2009.037 1 Journal of Applied Biological Chemistry, v.52, no.4, pp.216 - 220 Journal of Applied Biological Chemistry 52 4 216 220 scopus kci ART001407545 2-s2.0-77953526348 Article ABTS radical scavenging activity Aldo-keto reductase family 1 B10 Aldose reductase-like 1 Anti-cancer Antioxidant