Kim, Sehoon Ohulchanskyy, Tymish Y. Bharali, Dhruba Chen, Yihui Pandey, Ravindra K. Prasad, Paras N. 2024-01-20T21:03:16Z 2024-01-20T21:03:16Z 2021-09-03 2009-07-23 1932-7447 https://pubs.kist.re.kr/handle/201004/132304 We report a novel nanoassembly formulation for photodynamic therapy, which is composed of covalently iodine-concentrated organically modified silica (ORMOSIL) nanoparticles (diameter < 30 nm) and a hydrophobic photosensitizer embedded therein. Comparative studies with iodinated and noniodinated nanoparticles have demonstrated that the intraparticle external heavy-atom effect on the encapsulated photosensitizer molecules significantly enhances the efficiency Of O-1(2) generation and, thereby, the in vitro PDT efficacy. English American Chemical Society DRUG Organically Modified Silica Nanoparticles with Intraparticle Heavy-Atom Effect on the Encapsulated Photosensitizer for Enhanced Efficacy of Photodynamic Therapy Article 10.1021/jp900573s 1 The Journal of Physical Chemistry C, v.113, no.29, pp.12641 - 12644 The Journal of Physical Chemistry C 113 29 12641 12644 scie scopus 000268139800006 2-s2.0-68049137482 Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Chemistry Science & Technology - Other Topics Materials Science Article DRUG photodynamic therapy nanoparticle heavy-atom effect