Pan, Cheol-Ho Kim, Eun Sun Um, Byung Hun Lee, Jae Kwon 2024-01-20T21:30:36Z 2024-01-20T21:30:36Z 2021-09-03 2009-06 1226-7708 https://pubs.kist.re.kr/handle/201004/132460 The effect of 4 seaweed extracts (Desmarestia viridis, Dictyopteris divaricata, Scytosiphon lomentaria, and Ishige okamurae) on pro-inflammatory mediators as well as nuclear factor (NF)-kappa B in the stimulated Raw 264.7 cells was investigated. They reduced iNOS and interlukin (IL)-1 beta expressions at transcription level. Of those, 3 extracts (D. divaricata, I. okamurae, and S. lomentaria) inhibited the COX-2 expression at translation level. I kappa B-alpha degradation was inhibited by D. divaricata and S. lomentaria extracts. Therefore, we concluded that the extracts from D. divaricata and S. lomentaria could inhibit the activation of murine macrophage through the blocking of NF-kappa B activation. English KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST NF-KAPPA-B RHEUMATOID-ARTHRITIS TRANSCRIPTION FACTOR NITRIC-OXIDE RAT OVARY INFLAMMATION INTERLEUKIN-1 ACTIVATION MICE ANTICOAGULANT Anti-inflammatory Mechanism of Seaweeds in Murine Macrophage Article 1 FOOD SCIENCE AND BIOTECHNOLOGY, v.18, no.3, pp.813 - 817 FOOD SCIENCE AND BIOTECHNOLOGY 18 3 813 817 scie scopus kci ART001354636 000267693600039 Food Science & Technology Food Science & Technology Article NF-KAPPA-B RHEUMATOID-ARTHRITIS TRANSCRIPTION FACTOR NITRIC-OXIDE RAT OVARY INFLAMMATION INTERLEUKIN-1 ACTIVATION MICE ANTICOAGULANT Desmarestia viridis Dictyopteris divaricata Scytosiphon lomentaria Ishige okamurae inducible nitric oxide synthase (iNOS) interlukin-1 beta cyclooxygenase (COX)-2 I kappa B proinflammatory cytokine anti-inflammation