Kim, Guk Bae Lee, Sang Joon 2024-01-20T21:35:39Z 2024-01-20T21:35:39Z 2022-01-25 2009-03 0021-9290 https://pubs.kist.re.kr/handle/201004/132663 Hemodynamics has been a very important factor in understanding and diagnosing various vascular diseases. Recently, the X-ray particle image velocimetry (X-ray PIV) method using speckle patterns of blood has been introduced as a new quantitative visualization method for blood flows without any seeding tracer or contrast agents. In this study, the peculiar optical characteristics of blood on the synchrotron X-ray imaging method, which were not presented in previous studies, were investigated in depth and systematically. The experimental conditions required for X-ray PIV application were found to be the distance between the sample and the scintillator (similar to 40cm), the thickening of the blood sample (> 0.3 min), and hematocrit (20.0-80.0%). In addition, we verified that the X-ray PIV method is reliable as an advanced flow velocimetry by comparing the flow rate evaluated from the X-ray PIV result and the input flow rate supplied from a syringe pump with an error of less than 1%. Through this study, based on the understanding of contrast enhancement mechanisms of speckle patterns from blood, we Could establish a trustworthy flow visualization method that can be used effectively in hemodynamic studies. (c) 2008 Elsevier Ltd. All rights reserved. English ELSEVIER SCI LTD Contrast enhancement of speckle patterns from blood in synchrotron X-ray imaging Article 10.1016/j.jbiomech.2008.11.037 1 JOURNAL OF BIOMECHANICS, v.42, no.4, pp.449 - 454 JOURNAL OF BIOMECHANICS 42 4 449 454 N scie scopus 000264507300007 2-s2.0-60549100292 Biophysics Engineering, Biomedical Biophysics Engineering Article SHEAR-STRESS WALL SHEAR FLOW ARTERY VELOCIMETRY MICROSCOPY RESPONSES DIAMETER Synchrotron X-ray imaging method X-ray PIV Contrast enhancement Speckle patterns of blood Flow velocimetry