Kang, Eunah Kim, Kwangmeyung Kwon, Ick Chan 2024-01-20T22:02:09Z 2024-01-20T22:02:09Z 2021-09-03 2009-02 1975-8456 https://pubs.kist.re.kr/handle/201004/132774 Molecular imaging is a bioimaging that can detect biochemically and genetically relevant events in molecular level in cells and tissues via quantitative imaging signal. Molecular imaging provides potential advantages to examine early diagnosis of specific diseases, to screen new candidates of a drug, to monitor therapeutic effects in real time, and to communicate with both diagnosis and therapeutics. These diverse advantages of molecular imaging can be allowed by development of nanoplatform technology. The nanoplatform-based probes for molecular imaging is widely investigated to grant multimodal molecular imaging and drug delivery together with medical imagings, which includes the issues of biocompatibility, targeting moiety, protease-specific peptide substrate, quenching/dequenching system etc. In this paper, nanoplatform-based probes are reviewed in aspects of cancer targeting for diagnosis and therapy and multimodal molecular imaging with inorganic/organic hybrid nanoparticles. Korean KOREAN MEDICAL ASSOC GLYCOL CHITOSAN NANOPARTICLES IN-VIVO PROTEASE ACTIVITY PROBE ATHEROSCLEROSIS VISUALIZATION TOMOGRAPHY Multifunctional Nanoparticles for Molecular Imaging Article 10.5124/jkma.2009.52.2.125 1 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, v.52, no.2, pp.125 - 134 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION 52 2 125 134 scie scopus kci other ART001316629 000263852600004 2-s2.0-79955802670 Medicine, General & Internal General & Internal Medicine Review GLYCOL CHITOSAN NANOPARTICLES IN-VIVO PROTEASE ACTIVITY PROBE ATHEROSCLEROSIS VISUALIZATION TOMOGRAPHY Bioimaging Multimodality Nanoparticles Activatable Targeting Biodistribution