Park, Byong-Gon Kwon, Seong-Chun Park, Gab-Man Ham, Jungyeob Shin, Woon-Seob Lee, Seokjoon 2024-01-20T22:04:51Z 2024-01-20T22:04:51Z 2021-09-03 2008-12-15 0960-894X https://pubs.kist.re.kr/handle/201004/132878 Two farnesylacetones, 311 and 312, major active constituents of Sargassum siliquastrum collected from the coast of the East Sea in Korea, showed a moderate vasodilatation effect on the basilar arteries of rabbits. Therefore, treatment with farnesylacetones 311 and 312 may selectively accelerate cerebral blood flow through dilatation of the basilar artery. (C) 2008 Elsevier Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD MARINE NATURAL-PRODUCTS BROWN ALGA ALZHEIMERS-DISEASE PLASTOQUINONES DERIVATIVES MICRACANTHUM ANTIOXIDANT NICARDIPINE SAGAMIANUM VASOSPASM Vasodilatation effect of farnesylacetones, active constituents of Sargassum siliquastrum, on the basilar and carotid arteries of rabbits Article 10.1016/j.bmcl.2008.10.103 1 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.18, no.24, pp.6324 - 6326 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 18 24 6324 6326 scie scopus 000261141100004 2-s2.0-56249116545 Chemistry, Medicinal Chemistry, Organic Pharmacology & Pharmacy Chemistry Article MARINE NATURAL-PRODUCTS BROWN ALGA ALZHEIMERS-DISEASE PLASTOQUINONES DERIVATIVES MICRACANTHUM ANTIOXIDANT NICARDIPINE SAGAMIANUM VASOSPASM Marine natural product Farnesylacetones Vasodilatation Basilar artery Cerebrovascular diseases