방태선 이경진 함인혜 부영민 김호철 이재성 최호영 2024-01-20T22:05:55Z 2024-01-20T22:05:55Z 2021-09-06 2008-12 1229-1765 https://pubs.kist.re.kr/handle/201004/132922 Objectives : This study was to analyze the content changes of β-asarone and α-asarone in A. gramineus according to its parts, extraction method, and fermentation. Methods : The change of β-asarone and α-asarone was analysed with GC/MS, IR, and NMR. Results : In A. gramineus, β-asarone and α-asarone in rhizome are 7 times and 4 times more than those in leaves respectively. And, in water extract of Acori Graminei Rhizoma, β-asarone was reduced to 77.8%-83.5%, and α-asarone was reduced to 69.4%-72.2% compared with 50% MeOH extract. The amounts of β-asarone and α-asarone were decreased apparently by 1 and 3 weeks fermantation with yeast activated solution. Conclusions : There was a change in the content of asarone pursuant to the medicinal part, extraction solvent, and fermentation. This result can be used as the basic data contributing to the stability of A. gramineus according to an appropriate clinical application. Korean 대한본초학회 석창포의 부위, 추출용매 및 발효에 따른 주요 성분 변화 연구 A Study on the Content Changes of β-asarone and α-asarone in Acorus gramineus According to its Parts, Extraction Solvent, and Fermentation Article 2 대한본초학회지, v.23, no.4, pp.149 - 157 대한본초학회지 23 4 149 157 kci ART001301433 Acorus gramineus β-asarone α-asarone fermentation Acorus gramineus β-asarone α-asarone fermentation