Park, Ji Yeon Ullapu, Punna Reddy Choo, Hyunah Lee, Jae Kyun Min, Sun-Joon Pae, Ae Nim Kim, Youseung Baek, Du-Jong Cho, Yong Seo 2024-01-20T22:31:41Z 2024-01-20T22:31:41Z 2021-09-03 2008-11 1434-193X https://pubs.kist.re.kr/handle/201004/133016 A novel synthetic method to prepare chalcones 2 and chroman-4-ones 3 by TMSOTf-promoted addition of alkynes 1 to various aldehydes has been developed. The ratios of chalcones 2, chroman-4-ones 3 and hydrated products 4 varied depending upon the substituents R (nBu, phenyl, H and TMS) on the alkynes 1. We also describe the transformation of the chalcones 2 to the corresponding chroman-4-ones 3 under basic conditions. ( (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) English WILEY-V C H VERLAG GMBH COUPLING REACTION ASYMMETRIC-SYNTHESIS FLAVANONES HYDRATION CHROMANONES ACID TMSOTf-Promoted Addition of Alkynes to Aldehydes: A Novel Synthesis of Chroman-4-ones Article 10.1002/ejoc.200800782 1 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, v.2008, no.32, pp.5461 - 5469 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2008 32 5461 5469 scie scopus 000261756900014 2-s2.0-57349114904 Chemistry, Organic Chemistry Article COUPLING REACTION ASYMMETRIC-SYNTHESIS FLAVANONES HYDRATION CHROMANONES ACID Addition Aldehydes Alkynes Chromanone