Kim, Chul Young Lee, Hee Ju Lee, Mi Kyeong Ahn, Mi-Jeong Kim, Jinwoong 2024-01-21T00:05:49Z 2024-01-21T00:05:49Z 2021-09-02 2007-11 1615-9306 https://pubs.kist.re.kr/handle/201004/134014 Flavanone glycosides were successfully separated from the crude extract of Poncirus trifoliata by preparative centrifugal partition chromatography with a two-phase solvent system composed of ethyl acetate - acetonitrile - water (3:2:5, v/v/v). Naringin (50.0 mg), neoponcirin (16.8 mg), and poncirin (71.9 mg) were purified from the 524 mg crude extract in only one step. The purities of the isolated compounds were determined to be over 90% by HPLC analysis and their structures were elucidated by H-1 NMR, C-13 NMR, and ESI-MS. English WILEY-V C H VERLAG GMBH PREPARATIVE ISOLATION FRUIT EXTRACT RAT-KIDNEY NARINGIN SEPARATION ALKALOIDS DAMAGE One step purification of flavanone glycosides from Poncirus trifoliata by centrifugal partition chromatography Article 10.1002/jssc.200700168 1 JOURNAL OF SEPARATION SCIENCE, v.30, no.16, pp.2693 - 2697 JOURNAL OF SEPARATION SCIENCE 30 16 2693 2697 scie scopus 000250986700016 2-s2.0-36448944744 Chemistry, Analytical Chemistry Article PREPARATIVE ISOLATION FRUIT EXTRACT RAT-KIDNEY NARINGIN SEPARATION ALKALOIDS DAMAGE centrifugal partition chromatography naringin neoponcirin Poncirin Poncirus trifoliata