Park, Yeo Jin Kim, Hyoung Ja Lee, Sook Ja Choi, Ho-Young Jin, Changbae Lee, Yong Sup 2024-01-21T01:00:33Z 2024-01-21T01:00:33Z 2021-09-02 2007-07 0009-2363 https://pubs.kist.re.kr/handle/201004/134301 From the ethyl acetate fraction of the roots of Ostericum koreanum, a new chromone, 11-hydroxy-sec-O-glucosylhamaudol (1) along with the known compounds: four chromones, three coumarins, six phenolic compounds, and three quinic acids were isolated. These compounds were assessed for antioxidant activities in the DPPH radical and superoxide anion radical scavenging assay systems. Among isolates, 4-(2-hydroxy-vinyl)-benzene-1,2-diol (12) showed the most potent DPPH radical scavenging activity (IC50=4.80 +/- 0.62 mu g/ml) and superoxide anion radical scavenging activity (IC50=11.05 +/- 0.83 mu g/ml) in the xanthine/xanthine oxidase system. The antioxidant activities of 12 were comparable to those of quercetin and luteolin. English PHARMACEUTICAL SOC JAPAN CONSTITUENTS GLUCOSIDE A new chromone, 11-hydroxy-sec-O-glucosylhamaudol from Ostericum koreanum Article 10.1248/cpb.55.1065 1 CHEMICAL & PHARMACEUTICAL BULLETIN, v.55, no.7, pp.1065 - 1066 CHEMICAL & PHARMACEUTICAL BULLETIN 55 7 1065 1066 scie scopus 000248714600020 2-s2.0-34347376720 Chemistry, Medicinal Chemistry, Multidisciplinary Pharmacology & Pharmacy Pharmacology & Pharmacy Chemistry Article CONSTITUENTS GLUCOSIDE Ostericum koreanum (Umbelliferae) 11-hydroxy-sec-O-glucosylhamaudol chromome coumarin quinic acid antitoxidant activity