Kim, H.J. Jin, C. Lee, Y.S. 2024-01-21T01:01:43Z 2024-01-21T01:01:43Z 2021-09-02 2007-06 0253-3073 https://pubs.kist.re.kr/handle/201004/134355 In our continued search for biologically active compounds from traditional medicine, we found that ethyl acetate fraction from Inonotus obliquus showed potent antioxidant activities on three different cell-free bioassay systems. Bioassaydirected chromatographic fractionation of the ethyl acetate fraction from Inonotus obliquus afforded four phenolic compounds, 4-(3,4-dihydroxyphenyl) -(？)-3-buten-2-one (1), 3,4-dihydroxybenzaldehyde (2), protocatechuic acid (3) and caffeic acid (4) along with three sterols such as lanosterol (5), ergosterol peroxide (6) and 9,11-dehydroergosterol peroxide (7). Among isolates, phenolic compounds (1-4) were assessed for antioxidant activities. Almost phenolic compounds showed potent DPPH and superoxide anion radicals scavenging and lipid peroxidation inhibitory activities indicating that these phenolic compounds contribute to the antioxidative activities of /. obliquus. Compounds 2-3 and 7 were isolated for the first time from this plant. Korean Antioxidative activities of phenolic compounds isolated from Inonotus obliquus Article 1 Korean Journal of Pharmacognosy, v.38, no.2, pp.164 - 169 Korean Journal of Pharmacognosy 38 2 164 169 scopus kci ART001082965 2-s2.0-76749145574 Article Antioxidant Hymenochaetaceae Inonotus obliquus Phenolic compounds Sterols