Lim, Chang-Keun Lee, Jin-Seong Ha, Tai Hwan Kwon, Ick Chan Ahn, Cheol-Hee Park, Soo Young 2024-01-21T01:02:24Z 2024-01-21T01:02:24Z 2021-09-02 2007-05-20 1010-6030 https://pubs.kist.re.kr/handle/201004/134387 In this work, we report a novel stimuli-sensitive probe working on the principle of the cleavage-induced fluorescent change via hydrophilicity control. In our Si-Py-Ac-PEG probe, cleavage of hydrophilic PEG moiety in acidic environment induces hydrophobic interaction of pyrenes to increase their excimer emission. Our fluorescent probe (Si-Py-Ac-PEG) was successfully applied to the spotting microarray and nanoparticle suspension to demonstrate the potential of biological applications, i.e. protein chip and bioimaging. (C) 2006 Elsevier B.V. All rights reserved. English ELSEVIER SCIENCE SA PROBES DERIVATIVES MONOLAYERS DESIGN SENSOR Cleavage-induced fluorescence change via hydrophilicity control: A new strategy for biological application Article 10.1016/j.jphotochem.2006.12.002 1 JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, v.188, no.2-3, pp.149 - 154 JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 188 2-3 149 154 scie scopus 000246738900002 2-s2.0-34247126964 Chemistry, Physical Chemistry Article PROBES DERIVATIVES MONOLAYERS DESIGN SENSOR hydrophilicity control excimer emission cleavage microarray biomedical imaging