Yoo, Hye Hyun Park, Jeong Hill Kwon, Sung Won 2024-01-21T02:04:34Z 2024-01-21T02:04:34Z 2021-09-01 2006-11 0916-8451 https://pubs.kist.re.kr/handle/201004/135000 The lignan glycoside, tracheloside, was isolated from seeds of Carthamus tinctorius (Compositae) as an anti-estrogenic principle against cultured Ishikawa cells by employing a bioassay-linked HPLC-ELSD method. Tracheloside significantly decreased the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC50 value of 0.31 mu g/ml, a level of inhibition comparable to that of tamoxifen (IC50 = 0.43 mu g/ml). English TAYLOR & FRANCIS LTD ALKALINE-PHOSPHATASE ACTIVITY CANCER PHYTOESTROGENS TRANSFORMATION INVITRO CELLS An anti-estrogenic lignan glycoside, tracheloside, from seeds of Carthamus tinctorius Article 10.1271/bbb.60290 1 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, v.70, no.11, pp.2783 - 2785 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 70 11 2783 2785 scie scopus 000242455800031 2-s2.0-33751437715 Biochemistry & Molecular Biology Biotechnology & Applied Microbiology Chemistry, Applied Food Science & Technology Biochemistry & Molecular Biology Biotechnology & Applied Microbiology Chemistry Food Science & Technology Article ALKALINE-PHOSPHATASE ACTIVITY CANCER PHYTOESTROGENS TRANSFORMATION INVITRO CELLS Carthamus tinctorius tracheloside anti-estrogenic activity Ishikawa cell bioassay-linked HPLC-ELSD