Oh, Byung Soo Jung, Yeon Jung Oh, Young Jin Yoo, Young Sook Kang, Joon-Wun 2024-01-21T02:33:42Z 2024-01-21T02:33:42Z 2021-08-31 2006-08-31 0048-9697 https://pubs.kist.re.kr/handle/201004/135229 A research study to monitor the micropollutant levels present in the Han River, a major drinking water source for the Seoul Metropolitan district in Korea, was performed over a five-year period from 2000 to 2004, inclusive. Of the detected micropollutants, plithalates were found to be the major contaminants. In this study, the estrogenic activities of the detected plithalates and raw water samples contaminated with the pollutants were assessed by the E-screen assay using the MCF-7 breast cancer cell line. Of the plithalates, diethyl phthalate (DEP) and di(2-ethylhexyl) plithalate (DEHP) showed relatively high cell proliferation. Using DEP as a phthalate probe, three candidate processes, ozone alone, LTV alone, and the ozcme/UV combined, were evaluated for their efficiency in removing DEP and reducing its estrogenic activity. The ozone/UV process was shown to have the highest efficiency for the elimination of DEP and its by-products, leading to the complete mineralization of DER This study also found that the ozone/UV process is the best candidate to reduce the estrogenicity induced by DEP and its by-products. (c) 2006 Elsevier B.V. All rights reserved. English ELSEVIER SCIENCE BV E-SCREEN ASSAY HYDROGEN-PEROXIDE ENVIRONMENTAL-POLLUTANTS ULTRAVIOLET-RADIATION AQUEOUS-SOLUTIONS DRINKING-WATER KINETIC-MODEL DECOMPOSITION ESTERS COMBINATION Application of ozone, UV and ozone/UV processes to reduce diethyl phthalate and its estrogenic activity Article 10.1016/j.scitotenv.2006.02.051 1 SCIENCE OF THE TOTAL ENVIRONMENT, v.367, no.2-3, pp.681 - 693 SCIENCE OF THE TOTAL ENVIRONMENT 367 2-3 681 693 scie scopus 000240042700014 2-s2.0-33746334441 Environmental Sciences Environmental Sciences & Ecology Article E-SCREEN ASSAY HYDROGEN-PEROXIDE ENVIRONMENTAL-POLLUTANTS ULTRAVIOLET-RADIATION AQUEOUS-SOLUTIONS DRINKING-WATER KINETIC-MODEL DECOMPOSITION ESTERS COMBINATION ozone UV E-screen assay MCF-7 cell estrogenic activity phthalate