Park, HD Bae, JW Park, KD Ooya, T Yui, N Jang, JH Han, DK Shin, JW 2024-01-21T03:39:56Z 2024-01-21T03:39:56Z 2021-09-02 2006-02 1598-5032 https://pubs.kist.re.kr/handle/201004/135793 Sulfonated poly(ethylene glycol) (PEG-SO3) grafted polyrotaxanes (PRx-PEG-SO3) were prepared in order to utilize the unique properties of PEG-SO3 and the supramolecular structure of PRx, in which PEG-SO3 grafted alpha-cyclodextrins (alpha-CDs) were threaded onto PEG segments in a PEG-b-poly(propylene glycol) (PPG)-b-PEG triblock copolymer (Pluronic) chain capped with bulky end groups. Some of the PRx-PEG-SO3 demonstrated a higher anticoagulant activity in case of PRx-PEG-SO3 (P105), and compared with the control they showed a lower fibrinogen adsorption in PRx-PEG-SO3 (F68) and a higher binding affinity with fibroblast growth factor. The obtained results suggested that polyrotaxane incorporated with PEG-SO3 may be applicable to the surface modification of clinically used polymers, especially for blood/cell compatible medical devices. English POLYMER SOC KOREA PROTEIN ADSORPTION PLATELET-ADHESION AQUEOUS-SOLUTIONS POLYMER THERMODYNAMICS COPOLYMERS PREVENTION INTERFACES PLASMA Surface modification of polyurethane using sulfonated PEG grafted polyrotaxane for improved biocompatibility Article 10.1007/BF03219071 1 MACROMOLECULAR RESEARCH, v.14, no.1, pp.73 - 80 MACROMOLECULAR RESEARCH 14 1 73 80 scie scopus kci ART001190353 000235821200008 2-s2.0-33644828602 Polymer Science Polymer Science Article PROTEIN ADSORPTION PLATELET-ADHESION AQUEOUS-SOLUTIONS POLYMER THERMODYNAMICS COPOLYMERS PREVENTION INTERFACES PLASMA polyrotaxane sulforiated polyethylene glycol anticoagulant activity protein adsorption biocompatible