Ahn, MY Bae, HJ Kim, IS Yoo, EJ Kwack, SJ Kim, HS Kim, DH Ryu, KS Lee, HS Kim, JW Kim, I Lee, BM 2024-01-21T04:01:30Z 2024-01-21T04:01:30Z 2021-09-02 2005-12-10 1528-7394 https://pubs.kist.re.kr/handle/201004/135891 The mutagenic potential of the extracted components of Gryllus bimaculatus, a species of cricket, was evaluated using short-term genotoxicity tests including the Ames, chromosome aberration, and micronuclei tests. In a Salmonella typhimurium assay, G. bimaculatus extract did not produce any mutagenic response in the absence or presence of S9 mix with TA98, TA100, TA1535, and TA1537. Chromosome aberration testing showed that G. bimaculatus had no significant effect on Chinese hamster ovary (CHO) cells. In the mouse micronucleus test, no significant alteration in occurrence of micronucleated polychromatic erythrocytes was observed in ICR male mice intraperitoneally administered with G. bimaculatus extract at doses of 15, 150, or 1500 mg/kg. These results indicate that G. bimaculatus extract exerts no mutagenic effect in these in vitro and in vivo systems. English TAYLOR & FRANCIS INC INTERNEURONS BODY Genotoxic evaluation of the biocomponents of the cricket, Gryllus bimaculatus, using three mutagenicity tests Article 10.1080/15287390500182537 1 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, v.68, no.23-24, pp.2111 - 2118 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES 68 23-24 2111 2118 scie scopus 000233244800009 2-s2.0-28744458051 Environmental Sciences Public, Environmental & Occupational Health Toxicology Environmental Sciences & Ecology Public, Environmental & Occupational Health Toxicology Article INTERNEURONS BODY