김덕호 김병규 윤석준 강현재 2024-01-21T08:01:12Z 2024-01-21T08:01:12Z 2021-09-06 2003-12 1226-4873 https://pubs.kist.re.kr/handle/201004/138047 In biological cell manipulation, manual thrust or penetration of an injection pipette into an embryo cell is currently performed by a skilled operator, relying on visual feedback information only. Accurately measuring cellular forces is a requirement for minimally invasive cell injections. Moreover, the cellular force sensing is essential in investigating the biophysical properties for cell injury and membrane modeling studies. This paper presents cellular force measurements for the force feedback-based biomanipulation. Cellular force measurement system using piezoelectric polymer sensor is implemented to measure the penetration force of a zebra fish egg cell. First, measurement system setup and calibration are described. Second, the force feedback-based biomanipulation is experimentally carried out. Experimental results show that it successfully supplies real-time cellular force feedback to the operator at tens of uN and thus plays a main role in improving the reliability of biological cell injection tasks. Korean 대한기계학회 힘 피드백 기반의 세포조작을 위한 세포막 침습력 측정 Cellular Force Sensing for Force Feedback-Based Biological Cell Injection Article 2 대한기계학회논문집 A, v.27, no.12, pp.2079 - 2084 대한기계학회논문집 A 27 12 2079 2084 kci ART000995008