Oh, CH Dong, HG Lee, JS Lee, SC Hong, JH Cho, JH 2024-01-21T08:01:38Z 2024-01-21T08:01:38Z 2021-09-03 2003-12 0365-6233 https://pubs.kist.re.kr/handle/201004/138055 Synthesis of a new series of 1beta-methylcarbapenems with a substituted oxadiazolopyrrolidine moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of the substituent on the oxadiazole ring investigated. In particular, compounds 13 a and 13 c with ester and carbamoyl substituted oxadiazole moieties showed the most potent antibacterial activity English WILEY-V C H VERLAG GMBH Synthesis and antibacterial activity of 1 beta-methyl-2-(5-substituted oxadiazolo pyrrolidin-3-yl-thio)carbapenem derivatives Article 10.1002/ardp.200300768 1 ARCHIV DER PHARMAZIE, v.336, no.12, pp.567 - 572 ARCHIV DER PHARMAZIE 336 12 567 572 scie scopus 000187892900003 2-s2.0-0346394010 Chemistry, Medicinal Chemistry, Multidisciplinary Pharmacology & Pharmacy Pharmacology & Pharmacy Chemistry Article 1 beta-methylcarbapenem antibacterial activity substituent effect