Ryu, KE Rhim, H Park, CW Chun, HJ Hong, SH Kim, JJ Lee, YM 2024-01-21T08:01:41Z 2024-01-21T08:01:41Z 2021-09-03 2003-12 1598-5032 https://pubs.kist.re.kr/handle/201004/138056 Anion-substituted poly(vinyl alcohol) (PVA) membranes, carboxymethylated PVA (C-PVA), and sulfonated PVA (S-PVA) were prepared and the effects of these substitutions on the plasma protein adsorption were studied by one- and two-dimensional gel electrophoresis and immunoblotting. When Cuprophane was used as a negative control, the amount of total proteins bound to samples decreased in the order Cuprophane > PVA > C-PVA > S-PVA, which we attribute to the effects of the surface characteristics of the samples, such as their surface tensions and electrostatic properties, on the adsorption of proteins to the surfaces of the materials. The results revealed that albumin was the most abundant protein in all the samples. The proportion of adsorbed fibrinogen to S-PVA exceeded those of PVA and C-PVA, whereas S-PVA exhibited the lowest IgG adsorption affinity among the samples we studied. English SPRINGER BEHAVIOR FIBRINOGEN SURFACES BLOOD COMPLEMENT DENSITY Plasma protein adsorption to anion substituted poly(vinyl alcohol) membranes Article 10.1007/BF03218975 1 MACROMOLECULAR RESEARCH, v.11, no.6, pp.451 - 457 MACROMOLECULAR RESEARCH 11 6 451 457 scie scopus kci ART000980572 000220056500008 2-s2.0-1642333203 Polymer Science Polymer Science Article BEHAVIOR FIBRINOGEN SURFACES BLOOD COMPLEMENT DENSITY carboxymethylated poly(vinyl alcohol) sulfonated poly(vinyl alcohol) hemodialysis membrane plasma protein adsorption