Im, DS Cheong, CS Lee, SH 2024-01-21T08:10:59Z 2024-01-21T08:10:59Z 2021-09-03 2003-09-20 0253-2964 https://pubs.kist.re.kr/handle/201004/138229 The quaternary carbon-containing alcohols (1-6) were resolved enantioselectively by various lipases such as PFL (Pseudomonas fluorescens lipase), LAK (Pseudomonas fluorescens lipase), CRL (Candida rugosa lipase) and PCL (Pseudomonas cepacia lipase). The enzymatic resolution of racemic alcohol (+/-)-2 gave the excellent enantioselectivity in favor of (S)-2d in 99% ee, while those of the racemic alcohols (1, 3, 4, 5 and 6) gave the resolved alcohols with moderate to good enantioselectivity. Also, their absolute configurations were determined by chemical transformation to the known compounds. English KOREAN CHEMICAL SOC CHEMOENZYMATIC SYNTHESIS ENZYMES ESTERS Lipase-catalyzed remote kinetic resolution of quaternary carbon-containing alcohols and determination of their absolute configuration Article 1 BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.24, no.9, pp.1269 - 1275 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 24 9 1269 1275 scie scopus kci ART001190848 000185710100009 2-s2.0-0346964229 Chemistry, Multidisciplinary Chemistry Article CHEMOENZYMATIC SYNTHESIS ENZYMES ESTERS chiral tertiary nitriles lipase enantioselective resolution