Kim, Y. Min, H.-Y. Park, E.-J. Lee, Y.S. Jin, C. Lee, S.K. 2024-01-21T08:43:29Z 2024-01-21T08:43:29Z 2021-09-02 2003-06 1226-3907 https://pubs.kist.re.kr/handle/201004/138547 Since reactive oxygen radicals play an important role in carcinogenesis and other human diseases including neurodegenerative states, antioxidants present in natural products have received considerable attention for alleviation of these disease states. Therefore, in order to identify antioxidants in plant extracts, fifty-seven methanolic extracts derived from indigenous Korean plants were primarily assessed for potential to scavenge stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals. As a result, nine plant extracts were found to exhibit the DPPH free radical scavenging activity in the criteria of IC50 <40 μg/ml. In particular, the extracts of Melioma oldhami (IC50 = 0.1 μg/ml), Myrica rubra (IC50 = 16.2 μg/ml), Sympolocos paniculata (IC50 = 23.0 μg/ml) Carpinus laxiflora (IC50 = 25.1 μg/ml), and Cleyera japonica (IC50 = 26.2 μg/ml) showed a potent radical scavenging activity. Further study for the identification of active compounds from these lead extracts might be warranted. English carpinus laxiflora extract Cleyera japonica extract melioma oldhami extract myrica rubra extract plant extract scavenger unclassified drug antioxidant activity article carpinus laxiflora Cleyera japonica drug potency drug screening IC 50 medical assessment medicinal plant melioma oldhami myrica rubra nonhuman sympolocos paniculata Evaluation of the antioxidant potential of Korean indigenous plant extracts by free radical scavenging activity Article 1 Natural Product Sciences, v.9, no.2, pp.80 - 82 Natural Product Sciences 9 2 80 82 scopus kci other ART001204290 2-s2.0-0038503193 Article carpinus laxiflora extract Cleyera japonica extract melioma oldhami extract myrica rubra extract plant extract scavenger unclassified drug antioxidant activity article carpinus laxiflora Cleyera japonica drug potency drug screening IC 50 medical assessment medicinal plant melioma oldhami myrica rubra nonhuman sympolocos paniculata Carpinus laxiflora Cleyera japonica DPPH free radical scavenging activity Melioma oldhami Myrica rubra Sympolocos paniculata